Neuroendocrine Response to Oral Alcohol Administration

What is the purpose of this trial?

Brief Summary:
This study proposes to examine both the peripheral and central nervous system responses when light social drinkers and binge/heavy social drinkers are exposed to intravenous infusion of ethanol. The findings will provide a greater understanding of the brain mechanisms (cerebral blood flow and functional connectivity) underlying the association between stress, cortisol release, heart rate variability, alcohol craving, and alcohol stimulant and sedative effects. This knowledge could be significant in developing new therapies for the treatment of alcoholism.



Participation Guidelines

Ages: 21 - 45 years

Gender: Both


National Institute on Alcohol Abuse and Alcoholism

Dates: 12/05/2017 - 12/31/2017

Last Updated: 02/22/2018

Study HIC#: 2000022043

Get Involved

For more information about this study, contact:
Rachel Louise Hart
+1 888-978-7377
rachel.hart@yale.edu

If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email helpusdiscover@yale.edu or call 1-877-978-8348.

Trial Image

Investigators

Rajita Sinha

Principal Investigator

Sub-Investigators